Top 15 Health Tech Startups To Watch

Top 15 Health Tech Startups To Watch

Using biometric data, mobile apps, and wearables, these 15 health tech startups are bringing innovation to the health care industry by promoting healthier lives for patients.

Disruption in the healthcare industry and life sciences is well underway and shows no signs of slowing down. New health tech startups are jumping into the healthcare system at an astonishing pace and patient care is improving through earlier diagnoses, personalized health management, and better health outcomes. 

Far more than than a virtual primary care visit, digital health is using: 

  • Artificial intelligence, data science, machine learning, and blockchain technologies for research and diagnostics
  • Medical devices in the form of wearables and implantables to monitor chronic pain and to deliver medication
  • Mobile apps to promote well-being and to give the consumer more awareness and options for personal health management

Let’s take a look at how some leading health care startups are working to improve patient experiences.

Health Care Startups Innovating for Heart Disease

Health care worker holding glowing pill

According to the Centers for Disease Control and Prevention (CDC), heart disease is the No. 1 cause of death in the United States, representing 25% of the nation’s deaths. Heart disease is especially challenging because it’s irreversible and will continue to get worse. These health tech companies are innovating to change that.


An implantable device, the Barostim Neo is lauded for reducing symptoms and improving the quality of life for patients with heart disease. Developed by CVRx, the device relaxes the blood vessels, regulates heart rate, and reduces fluid in the body.

With $351.8 million in funding and a 97% success rate, according to the CVRx website, the future looks promising for this device and the patients who use it.

Omron Healthcare

Omron Healthcare is the first to market with a wristwatch-type blood pressure device. The HeartGuide™ blood pressure monitor is a wearable that tracks heart health in real time. Conveniently worn like a wristwatch, HeartGuide gives patients immediate feedback on the effects of their real-world activity. 

The HeartGuide medical device won numerous awards in 2019, including Time’s Best Inventions, CNET’s Innovation Award, and Techlicious’ Top Pick of CES. 

Health Care Startups Innovating for Cancer

Woman working at health tech startup

As the second-leading cause of death in the U.S., cancer is projected to claim over 600,000 lives this year, according to the American Cancer Society. The biggest culprit is lung cancer, causing over 22% of the deaths — three times that of the next deadliest cancer, colorectal cancer. These health care organizations are innovating earlier diagnoses and better treatment options.

Medial EarlySign

Medial EarlySign is bringing data analytics to providers in the health care system — along with lots of clinical data from its network. The innovation is in the way Medial EarlySign is using the data. By analyzing the large volume of data available, Medial EarlySign can identify individuals at high risk of getting specific diseases like colorectal or lung cancer.

By knowing their risk status, patients can make behavioral or dietary changes, are more prone to get regular checkups, and have the potential of avoiding disease or at least identifying early-stage symptoms when cancer is most treatable. Best of all, the data Medial EarlySign uses is the typical data stored in everyone’s electronic health record (EHR). No special tests or additional costs are involved.

SEngine Precision Medicine

Using mass data from digital medical records, SEngine Precision Medicine is spearheading clinical research for more effective cancer treatments and new drug discovery. By comparing a patient’s cancer cells with available therapies, SEngine promises to determine “the most effective and least toxic treatment options.”

Health Care Startups Innovating for Women’s Health

Health tech startup for women's health

Breast health, fertility issues, menopause symptoms, and more are all part of the field of women’s health services. These health tech startups are taking the lead in femtech, women’s health technologies.


According to their website, Welwaze’s product Celbrea® is “the first fully integrated breast health monitoring system.” Celbrea is a patch with sensors that connects to a mobile app and detects possible changes in a woman’s breast.

The device and app are intended to increase early detection and be used by women in addition to regular doctor exams and mammograms.

NextGen Jane

Still in beta testing, NextGen Jane promises to help women uncover early signs of cervical cancer, endometriosis, and other feminine diseases through their Smart Tampon platform.

Women receive kits that include an organic cotton tampon and a storage container to send their tampons to the company for analysis. Backed with $11.3 million in investor funding, NextGen Jane is a startup to watch.


Especially for working moms or mothers of multiple children, pumping breast milk can be a real hassle. Willow has developed a wearable breast pump, allowing women to harvest breast milk while attending to their normal tasks. Even better, Willow created a companion app to track the amount of milk being pumped over time and provide women with useful breastfeeding tips. 

Health Care Startups Innovating for Diabetes

The CDC published a sobering report showing 26.9 million adults in the United States have been diagnosed with diabetes and 7.3 million live with the disease undiagnosed. A staggering 88 million more are prediabetic. The innovations coming from these health tech startups bring a welcome relief to the nearly 35% of Americans with this condition.


The Omnipod, developed by Insulet, offers diabetics a wearable device that delivers continuous doses of insulin. Insulet also developed a mobile device to ensure users are getting the appropriate dosage.

The Omnipod’s waterproof and wireless design is not only convenient, but it also eliminates the need for injections. In addition, the companion device includes a calorie library of over 80,000 foods to help the user keep their diet on track.


A diabetic’s daily routine includes closely monitoring their glucose levels. Senseonics is the first health care company to develop an implantable CGM (continuous glucose monitor) device. Their Eversense system is built with a sensor implanted under the skin and uses a rechargeable transmitter and mobile app to measure glucose levels for up to 90 days.

Once your device is implanted, your data is easily shared with your health care provider.

Bigfoot Biomedical

As a caregiver to his 5-year-old son, the inventor of Bigfoot Medical is on a mission to make diabetes management easy and less intrusive in patients’ and caregivers’ lives. From measuring glucose to receiving insulin, Bigfoot promises a better solution — and it’s got $55 million in Series C financing to make it happen.

While not the first to market with a new device for CGM or insulin dosing, Bigfoot may be the first to market with a health care technology product that does both. With the personal story behind this company, this is a startup that will make headlines as it continues to innovate for its cause.

Health Care Startups Innovating Through Wearables and Smart Devices

Health tech wearable app design

These tech startups are going to market with digital health technologies that reflect current trends in wellness. Along with the proliferation of plant-based food innovations and consumer fitness equipment inventions, digital wellness tools are in high demand.


Connect a wrist strap with an embedded infrared sensor and a mobile app, and you’ve got Biostrap — a wearable device that analyzes sleep patterns, measures heart rates, calculates blood oxygen levels, and monitors respiratory rates.

Biostrap is a favorite among professional and amateur athletes and earned a spot as a semifinalist for the SleepTech Award from Sleep Foundation.


Stress has been linked to obesity, heart disease, Alzheimer’s, diabetes, depression, and more. The Apollo Neuro is a neuro-science powered wellness device that uses gentle vibrations to help you manage stress and improve your biometrics.

Apollo Neuro offers seven different modes of vibrations, so you can select the appropriate therapy to help you increase energy, improve focus, or wind down, depending on your needs.


For anyone taking multiple medications or even vitamins and supplements, EllieGrid keeps your pills organized and then takes the extra step of reminding you when to take them and when to get refills.

Using a smart pill box device connected to a mobile app, EllieGrid stores your medication in separate compartments and rings when it’s time to take your pills. It then flashes lights indicating which compartment contains the pills to take at that time, and how many to take. Premium versions offer historical records of the date and time medications are taken, and can even alert a caregiver of a missed dose.

Health Care Startups Innovating for Caregiving and Treatment

Gherry app screenshots


Sinq is a mobile-first platform built with the relationship between health insurance plan management, home health care providers, and patients in mind.

Using technology to enhance transparency, the Sinq platform can improve community health plans and help patients stay at home longer while receiving quality health services from informed care teams.


Vivi360 is an “insight-as-a-service” wearable developed by ViviHealth. Dedicated to recovery care and relapse prevention, Vivi360 monitors health indicators and applies machine learning to aid in care and recovery and identify warning signs of a potential relapse.

Armed with a GPS system, Vivi360 encourages support meeting attendance and alerts caregivers if the person in recovery is going into dangerous territory. Providers deliver more effective treatment programs through critical vital signs and behavioral insights.

Health Tech Startups Are Changing the Health Care System

Medical worker touching iPad screen with hovering digital charts

We’ve barely touched on the existing innovations disrupting the health care industry, and there’s sure to be more on the horizon. From treating illness to preventing disease, digital health tech is changing the way clinicians treat patients and how we take care of ourselves. 

December Labs is a leading tech company in the health care space, using health design thinking and accessibility processes to meet the highest quality assurance standards and ensure compliance with HIPAA regulations for EHR’s. 

We’ve helped our clients (many of them listed here) build cutting edge technology from the ground up in both iOS and Android frameworks, integrate wearables with mobile apps, and build cloud-based platforms to improve the health care system on a global scale. Contact us today and let’s partner on your next health care innovation.

News and things that inspire us

Receive regular(lish) updates about our latest work

Let's work together

Ready to rocket-fuel your product? Get in touch with our growth strategists to vet your idea or product and discuss options for approach and solutions.

Get in touch